Publications
Publications
Publications

Published! (Since 2009; students are in bold, last author = corresponding authorship. Researcher ID: D-5684-2012)


2017

Liuni P, Lento C, and Wilson DJ (2017) "Studying Enzyme Mechanisms Using Mass Spectrometry, Part 2: Applications" Chapter 8 in Mass Spectrometry in Chemical Biology: Evolving Applications, Editors: Norberto Peporine Lopes, Ricardo Roberto da Silva, Royal Society of Chemistry, ISBN: 978-1-78262-527-8 (link)

Lento C, Liuni P, and Wilson DJ (2017) "Studying Enzyme Mechanisms Using Mass Spectrometry, Part 1: Introduction" Chapter 7 in Mass Spectrometry in Chemical Biology: Evolving Applications, Editors: Norberto Peporine Lopes, Ricardo Roberto da Silva, Royal Society of Chemistry, ISBN: 978-1-78262-527-8 (link)

Deng B, Zhu S, Macklin AM, Xu J, Lento C, Sljoka A, and Wilson DJ (2017) "Suppressing Allostery in Epitope Mapping Experiments Using Millisecond Hydrogen/Deuterium Exchange Mass Spectrometry", mAbs (link)

Brown KA and Wilson DJ (2017) "Bottom-Up Hydrogen Deuterium Exchange Mass Spectrometry: Data Analysis and Interpretation", Analyst (link)

Zhu S, Khatun R, Lento C, Sheng Y, and Wilson DJ (2017) "Enhanced Binding Affinity via Destabilization of the Unbound State: A Millisecond Hydrogen / Deuterium Exchange Study on the Interaction Between p53 and a Pleckstrin Homology Domain", Biochemistry (link)

Resetca D and Wilson DJ (2017) "Mapping Ligand Binding Using Microfluidics-enabled Millisecond Timescale Hydrogen-deuterium Exchange", International Journal of Mass Spectrometry (link)

Lento C and Wilson DJ (2017) "Unravelling the Mysteries of Sub-second Biochemical Processes Using Time-Resolved Mass Spectrometry", Analyst (link)

Lento C, Zhu S, Brown KA, Knox R, Liuni P, and Wilson DJ (2017) "Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics", Journal of Visualized Experiments (link)

 

2016

Brown KA, Sharifi S, Hussain R, Donaldson L, Bayfield MA, and Wilson DJ (2016) "Distinct Dynamic Modes Enable the Engagement of Dissimilar Ligands in a Promiscuous Atypical RNA Recognition Motif", Biochemistry (link)

Balachandran N, Heimhalt M, Liuni P, Frederick To, Wilson DJ, Junop MS, and Berti PJ (2016) "Potent Inhibition of 3-Deoxy-d-arabinoheptulosonate-7-phosphate (DAHP) Synthase by DAHP Oxime, a Phosphate Group Mimic", Biochemistry (link)

Day C, Saldarriaga A, Tilley M, Hunter H, Organ MG, and Wilson DJ (2016) A Single-Stage, Continuous High-Efficiency Extraction Device (HEED) for Flow Synthesis", Organic Process Research & Development (link)

Deng B, Lento C, and Wilson DJ (2016) "Hydrogen Deuterium Exchange Mass Spectrometry in Biopharmaceutical Discovery and Development - A Review", Analytica Chimica Acta (link)

Donovan KA, Zhu S, Liuni P, Peng F, Kessans SA, Wilson DJ and Dobson RC (2016) "Conformational Dynamics and Allostery in Pyruvate Kinase", The Journal of Biological Chemistry (link)

Zhu S, Campbell JL, Chernushevich I, Le Blanc JC, Wilson DJ (2016) "Differential Mobility Spectrometry-Hydrogen Deuterium Exchange (DMS-HDX) as a Probe of Protein Conformation in Solution", JASMS (link)

Ball DP, Lewis AM, Williams D, Resetca D, Wilson DJ and Gunning PT (2016) "Signal transducer and activator of transcription 3 (STAT3) inhibitor, S3I-201, acts as a potent and non-selective alkylating agent", Oncotarget (link)

Lento C, Ferraro M, Wilson DJ and Audette GF (2016) "HDX-MS and deletion analysis of the type 4 secretion system protein TraF from the Escherichia coli F plasmid", FEBS Letters, 590(3):376-86 (link)

Wilson DJ (2016) "Millisecond Hydrogen Exchange" Chapter 5 in Hydrogen Exchange Mass Spectrometry of Proteins: Fundamentals, Methods, and Applications, Editor: David D. Weis, John Wiley and Sons, Inc., ISBN: 978-1-118-61649-9 (link)

 

2015

Lento C, Wilson DJ and Audette GF (2015) "Dimerization of the type IV pilin from Pseudomonas aeruginosa strain K122-4 results in increased helix stability as measured by time-resolved hydrogen-deuterium exchange", Structural Dynamics (link)

Liuni P, Deng B and Wilson DJ (2015) "Comparing equilibrium and kinetic protein unfolding using time-resolved electrospray-coupled ion mobility mass spectrometry", Analyst (link)

Zhu S, Shala A, Bezginov A, Sljoka A, Audette G and Wilson DJ (2015) "Hyperphosphorylation of intrinsically disordered tau protein induces an amyloidogenic shift in its conformational ensemble", PLoS One (link)

Bao J, Krylova SM, Cherney LT, Le Blanc JC, Pribil P, Johnson PE, Wilson DJ and Krylov SN (2015) "Pre-equilibration kinetic size-exclusion chromatography with mass spectrometry detection (peKSEC-MS) for label-free solution-based kinetic analysis of protein-small molecule interactions", Analyst, 140(4):990-4 (link)

Eiring A, Page B, Kraft I, Mason C, Vellore N, Resetca D, et al. (2015) "Combined STAT3 and BCR-ABL1 Inhibition Induces Synthetic Lethality inTherapy-Resistant Chronic Myeloid Leukemia", Leukemia (link)

Lento C, Audette GF and Wilson DJ (2015) "Time-resolved electrospray mass spectrometry — a brief history", Canadian Journal of Chemistry (link)

 

2014

Liuni P, Romanov V, Binette MJ, Zaknoun H, Tam M, Pilon P, Hendrikse J and Wilson DJ (2014) "Unambiguous characterization of analytical markers in complex, seized opiate samples using an enhanced ion mobility trace detector-mass spectrometer", Analytical Chemistry, 86(21):10772-9 (link)

Resetca D, Haftchenary S, Gunning PT and Wilson DJ (2014) "Changes in signal transducer and activator of transcription 3 (STAT3) dynamics induced by complexation with pharmacological inhibitors of Src homology 2 (SH2) domain dimerization", The Journal of Biological Chemistry, 289(47):32538-47 (link)

Bao J, Krylova SM, Cherney LT, LeBlanc JC, Pribil P, Johnson PE, Wilson DJ and Krylov SN (2014) "Kinetic size-exclusion chromatography with mass spectrometry detection: an approach for solution-based label-free kinetic analysis of protein-small molecule interactions", Analytical Chemistry, 86(20):10016-20 (link)

Zinck N, Stark AK, Wilson DJ and Sharon M (2014) "An improved rapid mixing device for time-resolved electrospray mass spectrometry measurements", ChemistryOpen (link)

Liuni PZhu S and Wilson DJ (2014) "Oxidative Labeling with Mass Spectrometry for Studying Protein Structure, Folding, and Dynamics", Antioxidants and Redox Signalling (link)

 

2013

Rob T, Gill PK, Golemi-Kotra D and Wilson DJ (2013) "An electrospray ms-coupled microfluidic device for subsecond hydrogen/deuterium exchange pulse-labelling reveals allosteric effects in enzyme inhibition", Lab on a Chip, 13(13), 2528-32 (link)

Sljoka A and Wilson DJ (2013) "Probing Protein Ensemble Rigidity and Hydrogen-Deuterium exchange", Physical Biology, 10(5):056013 (link)

Resetca D and Wilson DJ (2013) "Characterizing rapid, activity-linked conformational transitions in proteins via sub-second hydrogen deuterium exchange mass spectrometry", FEBS Journal, 280(22), 5616-5625, front cover feature (link)

Liuni P, Olkhov-Mitsel E, Orellana A and Wilson DJ (2013) "Measuring Kinetic Isotope Effects in Enzyme Reactions Using Time-Resolved Electrospray Mass Spectrometry", Analytical Chemistry, 85(7), 3758-64 (link)

 

2012

Liuni P, Jaganathan A and Wilson DJ (2012) "Conformer Selection and Intensified Dynamics During Catalytic Turnover in Chymotrypsin", Angewandte Chemie Int. Ed., 51(38), 9666-9669 (link)

Rob T, Liuni P, Gill PK, Zhu S, Balachandran N, Berti PJ and Wilson DJ (2012) "Measuring Dynamics in Weakly Structured Regions of Proteins Using Microfluidics-Enabled Subsecond H/D Exchange Mass Spectrometry", Analytical Chemistry, 84(8), 3771-3779 (link)

Liang Y, Ore MO, Morin S, and Wilson DJ (2012) "Specific Disruption of Transthyretin(105-115) Fibrilization Using "Stabilizing" Inhibitors of Transthyretin Amyloidogenesis", Biochemistry, 51(16), 3523-3530 (link)

Rob T and Wilson DJ (2012) "Time-resolved Mass Spectrometry for Monitoring Millisecond Time-scale Solution Phase Processes", European Journal of Mass Spectrometry,18(2), 205-214 (link)

 

2011

Bao J, Krylova S, Wilson DJ, Reinstein O, Johnson P and Krylov SN (2011) "Kinetic Capillary Electrophoiresis with Mass-Spectrometry Detection (KCE-MS) Facilitates Label-Free Solution-Based Kinetic Analysis of Protein-Small Molecule Binding", ChemBioChem, 12(17), 2251-2254 (link)

Liuni P and Wilson DJ (2011) "Understanding and optimizing electrospray ionization techniques for proteomic analysis", Expert Review of Proteomics, 8(4), 197-209 (link)

Wilson DJ and Heffernan JM (2011) "The Undead: A Plague on Mankind or a Powerful New Tool for Epidemiological Research?" a chapter in Mathematical Modeling of Zombies, Editor: Robert Smith, University of Ottawa Press, Ottawa, ON.

 

2010

Liang Y, Jasbi SZ, Morin S, and Wilson DJ (2010) "Rational Manipulation of Amyloidogenesis Using an Atomic Level Map of Peptide-Fibril Interactions", Biochemistry 49(28), 5829-31 (link)

Liuni P, Rob T and Wilson DJ (2010) "A Microfluidic Reactor for Rapid, Low Pressure Proteolysis with On-Chip Electrospray Ionization", Rapid Communications in Mass Spectrometry, 24(3), 315 – 320 (link)

Wilson DJ (2010) "Microfluidic Devices for Studying Kinetics" Chapter 3 in Microfluidic Devices in Nanotechnology: Fundamental concepts, Invited, Editor: Challa Kumar, John Wiley and Sons, Inc., Hoboken, NJ.; ISBN: 978-0-470-47227-9 (link)

 

2009

Liang Y, Haftchenary S, Jasbi SZ, Morin S and Wilson DJ (2009) "Binding Interactions in Early and Late-stage Amyloids of TTR105-115", Biophysical Chemistry, 144(1), 1-8 (link)

Rob T and Wilson DJ (2009) "A Versatile Microfluidic Chip for Millisecond Time-Scale Kinetic Studies by Electrospray Mass Spectrometry", JASMS, 20(1), 124-30 (link)

Ferguson PL, Kuprowski MC, Boys BL, Wilson DJ, Pan J and Konermann L (2009) "Protein Folding and Protein-Ligand Interactions Monitored by Electrospray Mass Spectrometry", Current Analytical Chemistry, 5(2), 186-204 (link)

Konermann L, Pan J, and Wilson DJ (2009) "Biochemical Reaction Kinetics Studied by Time-Resolved Electrospray Ionization Mass Spectrometry" Chapter 5 in Protein Mass Spectrometry, Editor: J. Whitelegge. Series: Comprehensive Analytical Chemistry;  Elsevier, Amsterdam, The Netherlands. ISBN-13: 978-0444530554

978-1-78262-527-8